艾叶是我国传统中药，其化学成分多样，包含有挥发油类、黄酮类、萜类、苯丙素类、有机酸类和甾体 类等多种化学成分。现代研究表明，艾叶具有抗炎、抗菌、抗氧化、免疫调节、抗肿瘤、促凝血和抗凝血等药 理作用。该文通过对艾叶的化学成分、药理作用的研究内容进行总结，并结合中药质量标志物概念，从植物亲 缘学、中药药性药效、产地、采收时期、陈化年份、炮制方法及化学成分特有性、溯源性、可测性等方面预测 分析艾叶的质量标志物，以期为建立全面科学的艾叶质量控制体系提供参考依据。

Artemisiae Argyi Folium is a traditional Chinese medicinal herb with diverse chemical components， including volatile oils，flavonoids，terpenoids，phenylpropanoids，organic acids，and steroids. Modern studies have shown that Artemisiae Argyi Folium possesses various pharmacological effects， such as anti-inflammatory， antibacterial，antioxidant，immunomodulatory，antitumor，pro-coagulant，and anticoagulant activities. This article summarizes the chemical composition and pharmacological effects of Artemisiae Argyi Folium， and based on the concept of quality markers in traditional Chinese medicine， predicts and analyzes its potential quality markers from perspectives such as plant phylogenetics，medicinal properties and efficacy，geographical origin，harvesting period， aging duration， processing methods， as well as the specificity， traceability， and measurability of chemical components. The aim is to provide a reference for establishing a comprehensive and scientific quality control system for Artemisiae Argyi Folium.

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河南省重大专项（221100310400）；岐黄学者项目（国中医药人教函 2022-6）；河南省重点科技计划项目（232301420019）；河南省杰出 外国专家工作室项目（38103029-2024）；河南省中医药科学研究专项（2024ZYZD15）