[关键词]
[摘要]
滁菊是菊科多年生的草本植物,是“四大名菊”之一,以花序入药,含有黄酮类、挥发油、萜类、酚酸 类、多糖类等成分,具有较高的药用和保健价值。该文在对滁菊化学成分、药理作用综述的基础上,围绕中药 质量标志物的概念,从植物亲缘学和化学成分特有性、传统药性、化学成分可测性、代谢组学和网络药理学、 谱效关系、干燥方式等方面对滁菊的质量标志物进行预测分析,发现牛磺酸、谷氨酸、咖啡酰基奎宁酸、β- 芹子烯、芹菜素等成分可作为滁菊质量标志物,以期为滁菊的质量评价研究提供依据。
[Key word]
[Abstract]
Chrysanthemum morifolium‘Chuju is a perennial herbaceous plant of the Asteraceae family. It is one of the “Four Famous Chrysanthemums”. Its inflorescence is used as medicine, which contains flavonoids, volatile oils, terpenes,phenolic acids,polysaccharides and other components,and has high medicinal and health care value. Based on the review of the chemical composition and pharmacological effects of Chrysanthemum morifolium ‘Chuju’,this paper focused on the concept of quality marker of traditional Chinese medicine, further predicted and analyzed the quality markers of Chrysanthemum morifolium‘Chuju’from the aspects of plant parentage and chemical composition specificity, traditional medicinal properties, measurability of chemical composition, metabolomics and network pharmacology, spectrum-effect relationships, different drying methods. It was found that taurine, glutamic acid, caffeoylquinic acid,β-apilene,apigenin can be used as quality-marker index of Chrysanthemum morifolium‘Chuju’. The aim of this study is to provide a basis for the quality evaluation of Chrysanthemum morifolium‘Chuju’.
[中图分类号]
R282.71
[基金项目]
国家自然科学基金面上项目(82074085);安徽省中青年教师培养行动学科(专业)带头人培育项目(DTR2023084);职业教育提质培优 行动计划项目(2021tjpzxkfkc08)