连翘为临床常用的清热解毒类中药，主要含有苯乙醇苷类、木脂素类、萜类及挥发油、黄酮类等化学成 分。大量研究证实连翘具有抗炎、抗菌、抗病毒、抗癌等多种药理作用，且安全性较高。该文系统综述了连翘 的化学成分、药理作用及安全性的研究进展，以总结连翘的相关研究成果，并为其进一步的开发研究和临床应 用提供思路。

Forsythiae fructus，a traditional Chinese medicine for heat clearing and detoxifying，is commonly used in clinic. It mainly contains phenylethanol glycosides， lignans， terpenoids， volatile oils， flavonoids and other chemical components. Numerous studies have confirmed that forsythiae fructus has anti-inflammatory，antibacterial， antiviral，anti-cancer and other pharmacological effects. Moreover，it has high safety. In this paper，the chemical composition，pharmacological action and safety of forsythiae fructus were reviewed. The aim of this study is to collect the relevant research achievements of forsythiae fructus，and to provide ideas and references for its further research and clinical application.

R284.1；R285.5

广东省实验室建设项目（2023B1212070029）；广东省重大人才工程项目（210183503006）。