抽动障碍是儿童常见的神经精神障碍性疾病，也是危害儿童健康的严重慢性疾病之一。叶天士“阳化内 风”学说认为，水不涵木、脾虚肝亢、木郁火炽而引动内风，筋则妄动。虫类药物具有“风性”，擅走窜，具 有益肾填精、平肝息风、化痰镇痉、宣风泻热、通络逐瘀之效，治疗儿童抽动障碍疗效确切。现代药理研究表 明，虫类药物能从抗惊厥、调节神经递质、抑制神经炎症、调节免疫等多角度治疗儿童抽动障碍。该文基于 “阳化内风”理论浅析虫类药物在治疗儿童抽动障碍中的应用，可为中医药防治抽动障碍提供理论参考。

Tic disorder is a common neuropsychiatric disorder in children and one of the common serious chronic diseases that endanger children’ s health. According to YE Tianshi’ s theory of“yang transforms into internal wind”， water fails to nourish wood （kidney yin deficiency can not nourish liver wood）， spleen deficiency and liver hyperactivity，wood stagnation and intense fire cause internal wind，and leading to frenetic stirring of tendons. Insect drugs are considered to be“pathogenic wind” in terms of pathogenic factors，and the pain wanders unsteadily. They have the effects of tonifying the kidney and supplementing essence，calming the liver and suppressing wind， resolving phlegm and relieving spasm，dispelling wind and purging heat，dredging collaterals and removing blood stasis，which exert certain effects in treating children with tic disorder. Modern pharmacological studies have shown that insect drugs can treat children with tic disorders from multiple perspectives such as anti-convulsion，regulation of neurotransmitters，inhibition of neuroinflammation，and regulation of immunity. Based on the theory of“yang transforms into internal wind”，this paper analyzes the application of insect drugs in the treatment of children with tic disorder，which can provide theoretical reference for the prevention and treatment of tic disorder by traditional Chinese medicine.

R22；R272；R285

科技部国家重点研发计划项目 （2018YFC1704104）；四川省中医药管理局项目 （2023MS505）；四川省教育厅一般项目 （17ZB0157）。