目的 优选北沙参茎叶中黄酮类化合物的提取条件。方法 采用超声波提取北沙参茎叶中的黄酮类化合物，以得率为指标，在单因素试验基础上采用正交试验优选提取条件。结果 提取条件为乙醇浓度:70 %，温度:70 ℃，时间:40 min，料液比为1∶30时，北沙参茎叶总黄酮得率最高，达3.31 %。结论 所用方法为北沙参茎叶中黄酮类化合物的提取条件提供了科学依据。

Objective To optimize the extraction condition for flavonoids from stems and leaves of Glehnia littoralis. Methods The flavonoids in stems and leaves of Glehnia littoralis were extracted with ultrasonic-assisted method . On the basis of single factor experiment，the orthogonal test was adopted to optimize the extraction condition with the yield rate as indicator. Results The optimal extraction condition was as follows:70 % of ethanol concentration，extraction temperature at 70 ℃，extraction time being 40 min，and the material-liquid ratio at 1 ∶ 30. Under the optimal condition，the extraction rate of total flavonoids from stems and leaves of Glehnia littoralis could be the highest，and reached 3.31 %. Conclusion The established methods will provide scientific basis for the optimal extraction condition of flavonoids from stems and leaves of Glehnia littoralis.

R284.1

山东省中医药科技发展计划项目(2009-264)。