[关键词]
[摘要]
目的 探讨岭南地区高血压病的中医用药规律,为辨证治疗高血压病提供有价值的参考。方法 采用频数统计方法,对1994~2009年岭南地区中医药治疗高血压病的102篇临床研究文献的用药规律进行统计分析。结果 (1)组方用药规律分析:用药类别由高到低频数依次为补虚药、平肝息风药、活血药、清热药、利水渗湿药、养心安神药、解表药、理气药;所用中药由高到低的频数依次为牛膝、茯苓、白芍、钩藤、杜仲、石决明、天麻、菊花、桑寄生等。(2)辨证用药规律(从高到低排序):①主证用方:肝火亢盛证:龙胆泻肝汤、天麻钩藤饮等;阴虚阳亢证:杞菊地黄丸、天麻钩藤饮、镇肝熄风汤等;痰湿壅盛证:半夏白术天麻汤、温胆汤、二陈汤等;阴阳两虚证:二仙汤、右归丸、金匮肾气丸等;肝阳上亢证:天麻钩藤饮、羚角钩藤汤、石决牡蛎汤等。②主证用药:肝火亢盛证:黄芩、栀子、钩藤、夏枯草、龙胆草、菊花等。阴虚阳亢证:牛膝、白芍、钩藤、山茱萸、熟地黄等。痰湿壅盛证:半夏、茯苓、陈皮、白术、天麻等。阴阳两虚证:山茱萸、熟地黄、杜仲、牛膝、淫羊藿等。肝阳上亢证:钩藤、牛膝、石决明、白芍、天麻等。结论 近15年岭南地区中医药治疗高血压病主要从虚、痰、瘀、火辨证治疗,是在辨证基础上运用古方加减为主。治疗上,着重以滋养肝肾、调整阴阳为主,健脾化痰祛湿也是重要的治法。
[Key word]
[Abstract]
Objective To explore the medication rule of Chinese herbal medicine for treatment of essential hypertension(EH) in the South of Five Ridges,and to provide valuable evidence for EH clinical practice. Methods Frequency analysis method was used to explore the medication rule of Chinese herbal medicine for treatment of EH after analyzing 102 associated traditional Chinese medical reports for treatment of EH in the South of Five Ridges,which were published from 1994 to 2009. Results (1)The following Chinese herbs were used for EH frequently in decreasing sequence,and they were herbs for tonifying deficiency,herbs for calming liver and subsiding wind,herbs for activating blood,herbs for clearing heat,herbs for promoting urination and draining dampness,herbs for tranquilizing by nourishing the heart,herbs for for relieving exterior syndrome and herbs for regulating qi. The frequently-used single herb was as follows(in decreasing sequence):Radix Achyranthis Bidentatae,Poria,Radix Paeoniae Alba,Ramulus Uncariae cum Uncis,Cortex Eucommiae,Concha Haliotidis,Rhizoma Gastrodiae,Flos Chrysanthemi,Herba Taxilli. (2)The application of Chinese herbal recipe for the syndromes was shown as Longdan Xiegan Decoction and Tianma Gouteng Decoction for the syndrome of hyperactive liver fire,Qiju Dihuang Pills,Tianma Gouteng Decoction and Zhengan Xifeng Decoction for the syndrome of yang hyperactivity due to yin deficiency,Banxia Baizhu Tianma Decoction,Wendan Decoction and Erchen Decoction for the syndrome of abundance of phlegm and dampness,Erxian Decoction,Yougui Pills,and Jinkui Shenqi Pills for the syndrome of yin-yang deficiency,Tianma Gouteng Decoction,Lingjiao Gouteng Decoction,and Shijue Muli Decoction for the syndrome of hyperactive liver yang. The medication of single herb for the syndromes was shown as Radix Scutellariae,Fructus Gardeniae,Ramulus Uncariae cum Uncis,Spica Prunellae,Radix Gentianae,and Flos Chrysanthemi for hyperactive liver fire syndrome,Radix Scutellariae,Radix Paeoniae Alba,Ramulus Uncariae cum Uncis,Fructus Corni,and Radix Rehmanniae Preparata for the syndrome of hyperactive yang due to yin deficiency,Rhizoma Pinelliae,Poria,Pericarpium Citri Reticulatae,and Rhizoma Gastrodiae for the syndrome of abundance of phlegm and phlegm,Fructus Corni,Radix Rehmanniae Preparata,Cortex Eucommiae,Radix Achyranthis Bidentatae,Herba Epimedii for the syndrome of yin-yang deficiency,Ramulus Uncariae cum Uncis,Radix Achyranthis Bidentatae,Concha Haliotidis,Radix Paeoniae Alba,and Rhizoma Gastrodiae for the syndrome of hyperactivitity of liver yang. Conclusion The analysis of recent 15-year Chinese medical reports for treatment of EH in the South of Five Ridges showed that the therapeutic principles are based on the pathogenesis of deficiency,phlegm,stasis and fire,and nourishing liver and kidney,regulating yin and yang,strengthening spleen to dampness are the main principles for treating EH by traditional Chinese Medicine.
[中图分类号]
R285.6
[基金项目]