目的 测定北沙参中重金属及有害元素含量，比较不同产地北沙参中的铜、铅、砷、镉、汞5种元素的含量。方法 采用火焰原子吸收法测定铜，采用石墨炉原子吸收法测定铅、镉，采用原子荧光光谱法测定砷、汞，并根据标准曲线计算其含量。结果 北沙参药材中铜、砷、汞含量均低于国家限量标准，安国地区北沙参药材中铅、镉含量高于国家限量标准。结论 建立的方法为科学制定中药材北沙参中重金属限量标准，提高北沙参药材的质量，保证临床安全用药提供科学依据。

Objective To determine the contents of heavy metals and harmful elements in Radix Glehniae from different producing areas and to compare the contents of Cu，Pb，As，Cd and Hg. Methods Cu was determined by flame atomic absorption spectrometry，Pb and Cd were determined by graphite atomic absorption spectrometry，and the contents of As，Hg were determined by atomic fluorescence spectroscopy. The contents were calculated simultaneously by calibration curves. Results The contents of Cu，As，Hg were lower than the national limit standard，but the contents of Pb，Cd in some areas were higher than the national limit standard. Conclusion This experiment provides the scientific basis for formulating the element limit standard，improving the quality of Radix Glehniae，and ensuring the clinical safety.

R284.1

山东省中医药科技发展计划项目(2009-259)。