目的 建立三虎痛风颗粒的质量标准。方法 采用TLC对方中的虎杖、葛根、防己、蒲公英、土牛膝、广金钱草进行定性鉴别；采用RP-HPLC测定虎杖苷、大黄素的含量。结果 TLC专属性强，简单可行。虎杖苷HPLC在0.042～0.336 μg范围内呈线性关系(r=0.9999)，平均回收率为101.33 %(RSD=1.24 %，n=6)。大黄素在0.0972～0.7776 μg范围内呈线性关系(r=0.9996)，平均回收率为101.13 %(RSD=1.73 %，n=6)。结论 本法操作简单、可靠、准确，重复性好，可用于本制剂的质量控制。

Objective To establish the quality standard of Sanhu Tongfeng granula. Methods Rhizoma Polygoni Cuspidati，Radix Puerariae，Radix Stephaniae Tetrandrae，Herba Taraxaci，Radix et Rhizoma Achyranthes and Herba Desmodii in the recipe were identified by TLC. The contents of polydatin and emodin were determined by RP-HPLC. Results TLC identification method was simple and feasible with high specificity. Polydatin had good linearity in a range of 0.042～0.336 μg(r=0.9999). The average recovery was 101.33 %，and RSD was 1.24 %(n=6). Emodin had good linearity in a range of 0.0972～0.7776 μg(r=0.9996). The average recovery was 101.13 %，and RSD was 1.73 %(n=6). Conclusion The method is simple，reliable and accurate with good repeatability，and can be applied as the quality control method for Sanhu Tongfeng granula.

R284.1

广西科技攻关项目(桂科攻-10124008-5)。