目的 研究紫花丹参和白花丹参二者谱学性质的差异。方法 综合运用紫外-可见光谱(UV-Vis)、红外光谱(FT-IR)和高效液相色谱(HPLC)3种方法研究紫花丹参和白花丹参5种不同提取部位的谱学行为，宏观比较谱图中峰的数目、形状和强度，以及5种主要活性物质的相对含量。结果 紫花丹参和白花丹参主要成分的种类基本相同，只是同类成分的含量有所差异。结论 确定了紫花丹参和白花丹参谱学性质的差别，为二者具有不同的药效学提供了分子依据。

Objective To investigate the differences of spectroscopy between Salvia miltiorrhiza Bge. and Salvia miltiorrhiza Bge. f. alba. Methods The spectroscopic properties of five extractions of S. miltiorrhiza Bge. and S. miltiorrhiza Bge. f. alba were studied by UV，IR and HPLC. The peak number，peak shape，peak intensity，and contents of five active compounds were compared broadly. Results The components existed in S. miltiorrhiza Bge. and S. miltiorrhiza Bge. f. alba were nearly the same，but the contents of the similar components were different. Conclusion The differences of spectroscopy between S. miltiorrhiza Bge. and S. miltiorrhiza Bge. f. alba are confirmed，which will provide the molecular proof of pharmacodynamics of S. miltiorrhiza Bge and S. miltiorrhiza Bge. f. alba.

R284.1

国家自然科学基金资助(81274012,81001603)；山东省农业良种工程资助项目([2007]217-12)。