目的 建立鸡骨草叶中3种黄酮碳苷含量的一测多评法（QAMS）。方法 通过外标法建立并计算鸡骨草叶3种黄酮碳苷的含量（实测值），并以芹 菜素-6，8-C-二葡萄糖苷为内标，建立其与芹菜素-6-C-阿拉伯糖-8-C-葡萄糖苷和芹菜素-6-C-葡萄糖-8-C-阿拉伯糖苷的相对校正因子（RCF），以该RCF计算芹菜素-6-C-阿 拉伯糖-8-C-葡萄糖苷和芹菜素-6-C-葡萄糖-8-C-阿拉伯糖苷的含量（计算值），并比较计算值与实测值之间的差异，实现一测多评。结果 芹菜素-6-C-阿拉伯糖-8-C-葡萄 糖苷和芹菜素-6-C-葡萄糖-8-C-阿拉伯糖苷与芹菜素-6，8-C-二葡萄糖苷之间的RCF分别为1.02、1.31，建立的RCF具有良好重现性和稳定性，20批鸡骨草叶中三种黄酮碳苷 含量的计算值与实测值的相对标准偏差＜3.5 %。结论 本文建立的QAMS是快速准确可行的，可用于鸡骨草叶的质量评价。

Objective To develop a method for the simultaneous determination of three flavones C-glycosides in the leaves of Herba Abri by quantitative analysis of multi-components by single marker（QAMS）. Methods The contents of three flavones C-glycosides in 20 batches of samples were determined by external standard method（ESM）. Using 6-C-glycopyranosyl-8-C-glycopyranosyl apigenin as the internal reference substance，the relative correction factors（RCF） of 6-C-arabinosyl-8-C-glycopyranosyl apigenin and 6-C-glycopyranosyl-8-C-arabinosyl apigenin to 6-C-glycopyranosyl- 8-C-glycopyranosyl apigenin were determined，and their contents were calculated according to the RCF. The method was evaluated by comparing the quantitative results between ESM and QAMS．Results The RCF values of 6-C-arabinosyl-8-C-glycopyranosyl apigenin，6-C-glycopyranosyl-8-C-arabinosyl apigenin to 6-C- glycopyranosyl-8-C-glycopyranosyl apigenin were 1.02 and 1.31，respectively. The RCF had good stability and reproducibility. No significant differences were found in the quantitative results between ESM and QAMS（RSD ＜ 3.5 %）. Conclusion The established QAMS is a fast， accurate and feasible method for evaluating the quality of the leaves of Herba Abri.

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