多囊卵巢综合征（PCOS）是一种生殖内分泌疾病，其心血管远期并发症的风险逐年增高，给患者健康带 来严重危害。激素失调与糖脂代谢紊乱、微环境稳态失衡、血管舒缩功能和内皮细胞功能损伤、血管生成和重 铸障碍及离子通道破坏等是 PCOS 并发心血管疾病（CVD）的重要发病机制。大量研究表明，中医药可通过改善 糖脂代谢、调节性激素、抗炎、促进血管生成、调节血管内皮功能等多角度防治 PCOS 并发 CVD。本文系统总 结了 PCOS 并发 CVD 的发病机制及中医药干预的研究内容，以期为中医药防治 PCOS 并发 CVD 的临床应用提 供更多参考。

Polycystic ovary syndrome （PCOS） is a reproductive endocrine disorder whose long-term risk of cardiovascular complications is increasing annually， posing a serious threat to patient health. Important pathogenic mechanisms underlying the development of cardiovascular disease （CVD） in PCOS include hormonal imbalances coupled with disorders of glucose and lipid metabolism，disruption of microenvironment homeostasis，impairment of vasomotor and endothelial cell function，abnormalities in angiogenesis and remodeling，and disruption of ion channels. A substantial body of research indicates that traditional Chinese medicine （TCM） can prevent and treat PCOS complicated by CVD through multiple approaches， such as improving glucose and lipid metabolism， regulating sex hormones，exerting anti-inflammatory effects，promoting angiogenesis，and modulating vascular endothelial function. This article systematically summarizes the pathogenesis of PCOS complicated by CVD and the research findings on TCM intervention mechanisms，aiming to provide further reference for the clinical application of TCM in the prevention and treatment of PCOS complicated by CVD.

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国家自然科学基金面上项目（82074259，82374286）；黑龙江省青年岐黄学者培养项目（黑中医药教函 〔2023〕 36号）。